Spatial Map of Bladder Cancer Reveals Hidden Tumor Environments and New Paths Toward Precision Therapy
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* Spatial profiling of muscle-invasive bladder cancer reveals how different tumor cell states are organized within individual tumors
* Bladder tumors are not simply "luminal" (more differentiated) or "basal" (less differentiated) but often contain both cell states arranged in distinct spatial patterns
* Luminal tumor cores and basal-like invasive regions respond differently to treatments
* Findings provide a framework that may inform precision therapy strategies tailored to the spatial tumor cell landscape of bladder cancer 
